As of October 4, 43 thousand 100 people were vaccinated with the first dose of AstraZeneca vaccine, 23 thousand 660 were vaccinated with the second dose, according to the Republican Center for Immunoprophylaxis.
According to the department, in the middle of this month the country will receive vaccines from the AstraZeneca company, those who received the first dose of the vaccine will be able to receive the second dose.
AstraZeneca’s expired vaccine is currently working with healthcare organizations on residues from the vaccine spill.
For information: According to research published in the medical journal The Lancet, the effectiveness of the AstraZeneca vaccine increased to 81.3% when the second dose of the vaccine was given 12 weeks after the first. In turn, with an interval between doses up to 3 months, i.e. 12 weeks, the antibody titer increased 4-fold. The results obtained indicate that a longer interval between dosing increases the immune response.
The longer the interval between the first and second doses of the AstraZeneca coronavirus vaccine, the stronger the immunity. This conclusion was made by representatives of the Anglo-Swedish company and scientists at Oxford University.
The recommended schedule is two doses (0.5 ml), according to the manufacturer’s instructions, the vaccine can be administered at intervals of 4-12 weeks. In light of the observed increase in the efficacy and immunogenicity of the vaccine with a longer interval between doses, WHO recommends an interval of 8-12 weeks. If the second dose is unintentionally delayed for more than 12 weeks, it should be given as soon as possible. Two doses are recommended for all vaccine recipients. (Preliminary Recommendations for the ChAdOx1-S [Recombinant] COVID-19 Vaccine. Interim guidance, updated April 21, 2021).
Based on the results of clinical studies of the University of Oxford COV001 and COV002, the administration of two doses of the COVID-19 vaccine (COrona VIrus Disease 2019 – the new coronavirus disease 2019), developed by AstraZeneca in cooperation with the University of Oxford, with a longer (up to 45 weeks) interval between doses.
Research data published by the University of Oxford as a preprint in The Lancet showed that high antibody titers persist for at least one year after the first dose of AstraZeneca’s COVID-19 vaccine.
Source: Kyrgyz National News Agency